Buffalo Bills vs Los Angeles Chargers Pick and Preview

Posted on December 22, 2023

AFC Conference Matchup

Point Spread: Bills -12.5 | Total Points: 44

Overall, the Bills have an above .500 record at 8-6. Helping their cause is the fact that they are in the midst of a two-game winning streak. In AFC action, the team is 4-5. Most recently, the Bills hosted the Cowboys. The game ended in a 31-10 win for Buffalo. Since they were favored by 2.5 against the Cowboys, the Bills secured an ATS victory. In the Bills’ most recent game, the under bettors finished with the win as the teams combined for 41 points. The pre-game line was set at 49.5.

This week, the Chargers will look to snap their current two-game losing streak with a victory over the Bills. Heading into action, the team has a below .500 record of 5-9. The Chargers will be looking to get back on track this week following their 63-21 loss to the Raiders. With a 42-point loss, the Chargers added a loss to their ATS record as well. They were 3-point underdogs prior to the game. With an over/under line of 36 points, the game saw a total of 84 points, going over the set line.

Buffalo Bills vs Los Angeles Chargers History

When looking back on the last three head-to-head matchups between Buffalo and Los Angeles, the Chargers hold the edge with a record of 2-1. Not only does the team have the better record, but they have won in convincing fashion, posting an average scoring differential of 11 points.

Through their last three road contests, the Bills offense has averaged 24 points per game while allowing an average of 26. Buffalo posted an overall record of 1-2 while going 1-2 ATS.
In their last five games at home, the Chargers have a straight-up record of 2-3 while going 2-3 vs the spread. The team’s offense averaged 18 points per game in these contests.
Looking back on the team’s last ten games as the underdog, the Chargers have a straight-up record of 1-9. Their record vs the spread in these games was 4-6.
In their last ten games as the betting favorite, the Bills have a straight-up record of 7-3 and an ATS mark of 5-5.

Notable Injuries

Buffalo Bills

Justin Shorter – Hamstring (Questionable)
Kaiir Elam – Ankle (Questionable)
Zach Davidson – Knee (Out)
Kameron Cline – Undisclosed (Out)
Tommy Doyle – Knee (Out)
Ty Johnson – Shoulder (Questionable)
Damien Harris – Neck (Out)
A.J. Epenesa – Ribs (Questionable)
Tre’Davious White – Achilles (Out)
Matt Milano – Lower Leg (Out)
Nyheim Hines – Knee (Out)
Jordan Phillips – Wrist (Out)
DaQuan Jones – Pectoral (Questionable)
Micah Hyde – Neck (Out)

Los Angeles Chargers

Corey Linsley – Heart (Out)
Nick Williams – Shoulder (Questionable)
Keenan Allen – Heel (Out)
Mike Williams – Knee (Out)
Joey Bosa – Foot (Questionable)
Will Clapp – Knee (Out)
Zack Bailey – Back (Out)
Tanner Muse – Knee (Questionable)
Justin Herbert – Finger (Out)
Chris Rumph II – Foot (Out)
Essang Bassey – Concussion (Questionable)
Nick Vannett – Back (Questionable)
Deane Leonard – Ankle/heel (Doubtful)
Raheem Layne – Knee (Out)
Andrew Trainer – Undisclosed (Out)
Amechi Uzodinma – Undisclosed (Out)

Keys To Victory: Buffalo Bills

Heading into week 16, the Bills feature as one of the league’s top-scoring offenses, maintaining an average of 27.1 points per game (6th). Buffalo currently ranks 12th in passing attempts and has an average of 7 yards per attempt (6th). With 244.6 passing yards per game, they are positioned 8th in the league. A key to the team’s offensive success is their effectiveness on the ground. On the season, the Buffalo offense is 8th in rush yards per attempt. This figure has led to an average of 132.3 yards per game.

Keys To Victory: Los Angeles Chargers

On the offensive side of the ball, the Chargers currently hold an average of 21.6 points per game, which places them at 15th in the NFL. With a passer rating of 98.5, Easton Stick is 12th at the position. This figure has come while throwing for 436 yards and three passing touchdowns. Running the ball has been tough for the Chargers all season, as they are just 27th in rush yards per game.

Betting Trends

In their last five games away from home, the Bills have a straight-up record of 2-3 while going 2-3 vs. the spread. The team averaged 26 points per game in this stretch.
Through their last three home contests, the Chargers’ offense has averaged 15 points per game while allowing an average of 28. Los Angeles posted an overall record of 1-2 while going 1-2 ATS.
Going back to their last three games as the underdog, the Chargers have a straight-up record of 0-3. But, their mark vs the spread was just 0-3.
Looking back on the team’s last ten games as the favorite, the Bills have a straight-up record of 7-3. Their record vs the spread in these games was 5-5.