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Buffalo Bills vs Cincinnati Bengals Pick and Preview

Joe Burrow

AFC Conference Matchup

Point Spread: Bengals -2 | Total Points: 49.5

Coming into to this week’s AFC matchup vs the Bengals, the Bills have an above .500 record at 5-3. The Bills are coming off a win in their last game, where they beat the Buccaneers with a score of 24-18. Even with a victory, the Bills couldn’t cover the spread against the Buccaneers, going in favored v 10. In the matchup with Tampa Bay, the pre-game over/under line was 42.5. The under hit, as they combined for 42 points.

As the Bengals prepare for this AFC matchup, the team has an overall record of 4-3. This includes riding a current three-game win streak. Against AFC opponents, they have a record of 0-3. In week 8, the Bengals hit the road to face the 49ers, coming away with a 31-17 win. In addition to winning the game, the Bengals managed to cover the spread as 4-point underdogs. Heading into the game, the over/under line was 44 points. As they combined for 48 points, the over hit.

Buffalo Bills vs Cincinnati Bengals History

The Bengals picked up a 27-10 over the Bills in their only head-to-head matchup last season. In their only head-to-head matchup, the teams scored 37 points, which fell below the over/under line of 48.5. The Bengals covered the spread in last year’s matchup. In last year’s win, the Bengals finished with 412 of total offense, with 172 coming in the running game and 240 through the air. On the other side, the Bills ended the game with 325 of offense.

In the last three head-to-head matchups, the Bengals are averaging 21 points per game, compared to the Bills at 15. These figures have led to Cincinnati posting a record of 2-1.

Notable Injuries

Buffalo Bills

  • A.J. Klein – Back (Questionable)
  • Justin Shorter – Hamstring (Out)
  • Josh Allen – Right Shoulder (Probable)
  • Damar Hamlin – Illness (Probable)
  • Kaiir Elam – Ankle (Out)
  • Tommy Doyle – Knee (Out)
  • Quintin Morris – Ankle (Probable)
  • Zach Davidson – Knee (Out)
  • Baylon Spector – Hamstring (Questionable)
  • Damien Harris – Neck (Out)
  • Dawson Knox – Wrist (Out)
  • Nyheim Hines – Knee (Out)
  • Tre’Davious White – Achilles (Out)
  • Matt Milano – Lower Leg (Out)
  • DaQuan Jones – Pectoral (Out)

Cincinnati Bengals

  • Devin Cochran – Knee (Out)
  • Akeem Davis-Gaither – Knee (Questionable)
  • Chase Brown – Hamstring (Out)
  • Devonnsha Maxwell – Knee (Out)
  • Charlie Jones – Thumb (Out)
  • Trey Hendrickson – Foot (Questionable)
  • Josh Tupou – Shoulder (Questionable)
  • Joe Mixon – Chest (Probable)
  • Orlando Brown Jr. – Groin (Questionable)
  • Tycen Anderson – Knee (Out)

Keys To Victory: Buffalo Bills

The Buffalo offense comes in with an average of 27.8 points per contest. This has the Bills sitting 4th in the NFL. In the passing game, the Bills are averaging 263.8 passing yards per game, which is 4th in the league. So far, 59.1% of their first downs have come through the passing game. A key aspect of the team’s strong offensive play has been their ability to run the ball. This year, the Bills are near the top of the league in both attempts and yards per game. Currently, the team is averaging 113.1 yards per game on the ground.

Keys To Victory: Cincinnati Bengals

The Cincinnati offense is currently positioned 20th in the league, scoring an average of 18.7 points per contest. In his seven games. Joe Burrow has thrown 10 touchdowns, which is 8th among quarterbacks. Additionally, he has 1513 passing yards, placing him 22nd in his position. A major reason for the team’s lack of offense is their inability to generate production with the rushing attack. Heading into today’s game, the team’s below-average number of rush attempts has turned into an average of just 79 rushing yards per game.

Betting Trends

  • When looking at their past ten road matchups, Buffalo has an ATS record of 4-6 while averaging 24 per game. The team went 6-4 overall in these games.
  • Cincinnati has played well in their previous three home games, going 2-1 straight up. In this stretch, they averaged 22 points per game while allowing 21. The team also performed well vs. the spread at 2-1.
  • Going back to their previous three games as the underdog, Buffalo has an ATS mark of 1-2 while going 1-2 straight up.
  • In their last ten games as the betting favorite, the Bengals have a straight up record of 8-2 and an ATS mark of 5-5.


  • Cincinnati Bengals 26 – Buffalo Bills 25
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