Game Preview

Arizona Cardinals vs Philadelphia Eagles Pick and Preview

DeVonta Smith

NFC Conference Matchup

Point Spread: Eagles -10.5 | Total Points: 48

This week, the Cardinals will look to snap their current two-game losing streak with a victory over the Eagles. Heading into action, the team has a below .500 record of 3-12. Last time they played, the Cardinals were handed a 27-16 loss by the Bears. In addition to their 11-point loss, the Cardinals also suffered a setback in their ATS record. They were 4.5-point underdogs at the start of the game. The game had an over/under line of 42.5 points, and both teams went beyond it, scoring a combined total of 43 points.

Coming into this week’s NFC matchup vs the Cardinals, the Eagles have an above .500 record at 11-4. The Eagles are coming off a win in their last game, where they beat the Giants with a score of 33-25. The Eagles secured the win, but they didn’t cover the spread against the Giants while being favored by 14. The game’s over/under line was 41.5 points, leading to the over hitting with a combined 58 points.

Arizona Cardinals vs Philadelphia Eagles History

In their only head-to-head matchup last season, the Eagles won by a score of 20-17. With their combined 37, the Cardinals and Eagles fell short of the over/under line of 48.5. The Cardinals covered the spread in this matchup. Offensively, the Eagles finished with 218 passing yards and 139 rushing yards in their win over the Cardinals. As for Arizona, they ended the game with 363 yards of total offense.

The last ten head-to-head matchups between the Cardinals and Eagles have gone in favor of the Cardinals, putting together a record of 6-4. In the last five head-to-head games between the Cardinals and Eagles, the average combined point total is 47 points per game. The over/under record in these matchups is 2-3.

Notable Injuries

Arizona Cardinals

  • Geoff Swaim – Calf (Out)
  • Pat Elflein – Hip (Out)
  • Marlon Mack – Achilles (Out)
  • Carlos Watkins – Bicep (Out)
  • Kyzir White – Biceps (Out)
  • Josh Woods – Undisclosed (Out)
  • Rashad Fenton – Undisclosed (Out)
  • Jonathan Ledbetter – Knee (Out)
  • L.J. Collier – Bicep (Out)
  • Marquise Brown – Heel (Questionable)
  • Leki Fotu – Hand (Questionable)
  • Bobby Price – Quad (Questionable)
  • Zaven Collins – Ankle (Questionable)
  • Victor Dimukeje – Foot (Questionable)
  • Hayden Howerton – Undisclosed (Out)
  • Garrett Williams – Knee (Questionable)
  • Jon Gaines II – Knee (Out)
  • Matt Hembrough – Back (Out)
  • Andre Chachere – Shoulder (Questionable)
  • Kyler Murray – Illness (Questionable)
  • Kevin Strong – Knee (Questionable)
  • Owen Pappoe – Ankle (Questionable)

Philadelphia Eagles

  • Devon Allen – Undisclosed (Out)
  • Nakobe Dean – Foot (Out)
  • Roderick Johnson – Undisclosed (Out)
  • Nicholas Morrow – Abdomen (Questionable)
  • Justin Evans – Knee (Out)
  • Zach Cunningham – Knee (Questionable)
  • Avonte Maddox – Pectoral (Questionable)
  • Darius Slay – Knee (Questionable)
  • Isaiah Rodgers Sr. – Suspension (Out)
  • Shaun Bradley – Achilles (Out)
  • Zech McPhearson – Achilles (Out)

Keys To Victory: Arizona Cardinals

Quarterback Kyler Murray will try to lead the Cardinals to a win despite being 10.5-point underdogs on the road. As a team, Arizona is averaging 18.3 points per game, placing them 23rd in the NFL. For the season, Murray is averaging 217 passing yards per game through the air. This figure has him sitting 33rd among quarterbacks. Murray comes in with a passer rating of 81.9 and is averaging 10.1 yards per completion. Against the Eagles, the team will look to get receiver Trey McBride involved in the passing game. This year, he is averaging 6.2 targets per game, leading to an overall receiving yards total of 743. When it comes to rushing, the Cardinals are averaging 4.9 yards per attempt while running the ball an average of 26.2 times per game. At 129.2 rushing yards per contest, they are 9th in the league.

Keys To Victory: Philadelphia Eagles

Led by quarterback Jalen Hurts, the team’s 7th-ranked scoring offense will need to be on top of their game to cover the spread as -10.5 point betting favorites. This season, he has completed 65.5% of his passes, leading an average of 242 yards per game in the passing attack. Overall, he is 9th among QB’s in passing yards and 9th in attempts. Against the Cardinals, the team will look to get receiver A.J. Brown involved in the passing game. This year, he is averaging 10.1 targets per game, leading to an overall receiving yards total of 1394. Philadelphia comes in with an average of 4.1 yards per rushing attempt and has an average of 30.9 attempts per game. In terms of total rushing yards, they are currently ranked 6th in the league.

Betting Trends

  • In their last three road games, Arizona has averaged 18 points per game while allowing 19. The team’s record in this stretch was 1-2 while going 2-1.
  • In their last three games at home, the Eagles have a straight-up record of 1-2 while going 1-2 vs. the spread. The team averaged 17 points per game in this stretch.
  • Looking back on the team’s last three games as the underdog, the Cardinals have a straight-up record of 1-2. Their record vs the spread in these games was 1-2.
  • As the betting favorite, the Eagles have an ATS mark of just 5-4-1 in their last ten games. Philadelphia posted a straight-up mark of 8-2 in these matchups.


  • Philadelphia Eagles 25 – Arizona Cardinals 21
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